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12,000+ certified
30+ countries

The world's most global institution in regenerative medicine

The Advanced Regenerative Medicine Certification

ISSCA’s flagship online certification — the one that carries the whole allogeneic field instead of a slice of it: MSCs, exosomes and cell-free biologics, NK cells and advanced immune therapies, GMP and COA auditing, regulatory reality, handling and technique, and clinical integration. 11 modules, 30 hours. Self-paced. Lifetime access.

4.8 from 500+ health professionals

With Keith L. March, MD, PhD & Rafael González, PhD — plus 7 ISSCA faculty

Pre-sale closes September 30, 23:59 UTC
11 Modules
30 Hours
Lifetime Access
17+ Years Leading Regenerative Medicine Globally
12,000+ Physicians Certified Globally
30+ Countries Worldwide

The flagship certification

Everything ISSCA teaches about allogeneic regenerative medicine, in one certification.

Most programmes teach a product. This one teaches the practice around it — the biology, the sourcing, the manufacturing behind the vial, the regulation, the technique and the integration. Eight domains, 11 modules, 30 hours.

Modules 01–02

Mesenchymal Stem Cells & Allogeneic Products

MSC sources compared — umbilical, adipose, dental pulp, placental — then donor selection, banking, expansion and viability, and what actually separates a clinical-grade product from a research-grade one.

Lessons include
Reading Product Specifications Like a Clinician · What “Allogeneic” Means at the Molecular Level

Module 03

Exosomes & Cell-Free Biologics

The 2026 update: exosome biology and the secretome concept, and the skill the market rewards most — telling a real exosome preparation from a product merely labelled as one.

Lessons include
Clinical Indications: Aesthetics, MSK, Neurology, Longevity · Dosing, Frequency and Stacking with Cellular Products

Module 08

NK Cells & Advanced Immune Therapies

NK cell biology, activation and allogeneic deployment — plus where the regenerative physician genuinely fits in the immune-therapy conversation, and where the honest answer is a referral.

Lessons include
CAR-T: Mechanism, Indications and Adjacencies · Referral Pathways, Co-Management and Informed Referral

Module 04

Manufacturing, GMP & the COA

How the product in your hand was made, and the Certificate of Analysis read line by line. The single most practical skill on this list — and the one that protects you from a bad lot.

Lessons include
Cold Chain, Shelf Life and Reconstitution Failure Modes · Lot-to-Lot Variability and Clinical Control

Module 05

Regulatory & Legal Reality

The global regulatory map — FDA, EMA, ANVISA, COFEPRIS, MFDS — and the HCT/P framework, taught as a structure to reason with. Never as advice about your own jurisdiction.

Lessons include
Marketing Claims, Off-Label Use and Informed Consent · Insurance, Liability and Documentation Hygiene

Module 06

Handling, Thawing & Preparation

The part no conference teaches: receipt protocols, chain of custody, thawing curves, viability checks and the reconstitution maths — plus the preparation failures that quietly ruin outcomes.

Lessons include
Receipt Protocols, Temperature Verification, Chain of Custody · Common Preparation Failures and How to Prevent Them

Module 07

Clinical Indications & Protocol Design

Six lessons — the widest module in the programme — across MSK, aesthetics, neurology and pain, and metabolic and longevity applications, ending in patient evaluation and therapy selection.

Lessons include
MSK: Joint, Tendon, Ligament · Special Cases and Complex Patient Profiles

Modules 09–11

Technique, Integration & Evidence

Routes of administration from intra-articular to intrathecal, image-guidance basics and recorded faculty demonstrations — then positioning, pricing, SOPs and how to read the literature critically.

Lessons include
Recorded Clinical Demonstrations from ISSCA Faculty · Measuring Outcomes That Justify the Investment

Get Certified

One certification. Eight clinical domains. 11 modules, 30 hours, self-paced, lifetime access.

Who this certification is for

Built for Licensed Physicians Who Want to Lead in Regenerative Medicine

Whether you already prescribe biologics or are entering the field — this program delivers the clinical framework to choose, use, defend and scale regenerative therapies.

Advanced Practicing Physicians

MDs already practicing regenerative medicine with autologous or basic biologics who want to raise the ceiling of their practice — integrating MSCs, exosomes, NK and CAR-T realities with clinical judgment.

Physicians Entering Regenerative Medicine

Specialists in aesthetics, orthopedics, internal medicine or longevity who want a clear, safe path into regenerative practice — without improvising, with clinical judgment from day one.

Clinical Leaders & Directors

Medical directors, clinic owners and department heads evaluating training for their team — leading the next decade of regenerative medicine in their institution.

Physician-Level Certification. Exclusive to licensed MDs.

What you'll master

Skills You'll Apply Immediately

Practical capabilities you'll have after completing this certification.

Integrate the 4 Advanced Cell Lines

MSCs, exosomes, NK cells and CAR-T — choose, sequence and combine the four advanced biologics in clinical protocols.

Read COAs Like a Manufacturer

Evaluate allogeneic products before you order them. Understand GMP, GTP, viability data and lot-to-lot variability.

Master Routes & Technique

IA, intralesional, IM, IV, transdermal, intrathecal — competence across every administration route the regenerative physician needs.

Design Protocols by Indication

Decision algorithms for MSK, aesthetics, neurology, pain, metabolic and longevity — ready to deploy Monday morning.

Grow a Sustainable Practice

Positioning, pricing, team training, SOPs and outcome measurement that turn regenerative services into a sustainable practice line.

Credential Your Expertise

Earn serialized ISSCA certification — recognized by practitioners in 30+ countries, exclusive to licensed physicians.

Complete curriculum

11 Modules • 30 Hours • Lifetime Access

A complete clinical path from applied functional biology to the integration of regenerative practice into a sustainable clinic.

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Total: 11 Modules | 30 Hours of Expert-Led Video Content | Downloadable Clinical Protocols | Lifetime Access

Launching in English · Spanish & Portuguese subtitles post-launch
ISSCA international faculty

Nine curated physicians and scientists.

Hand-picked from the global ISSCA faculty for clinical authority and teaching ability. Click any portrait for the full bio.

Everything Included in Your Certification

  • 11 Video Modules (30 Hours of Expert-Led Content)
  • Online Assessment
  • Serialized ISSCA Certification (digital + framable physical diploma)
  • 1 Year ISSCA Membership — $1,000 value, included
  • ISSCA App + Magazine + Experience Access
  • Lifetime Access · Future Updates Included
  • 14-Day Guarantee

Bonus: downloadable resources

  • Clinical Case Studies (PDF)
  • ISSCA Regenerative Protocols Kit (PDF)
  • COA Reading Reference Guide (PDF)
  • Routes of Administration Reference (PDF)
  • Indication-by-Indication Protocol Algorithm (PDF)
  • Cellgenic Product Catalog 2026 (PDF)
Get Certified
ISSCA Advanced Regenerative Medicine Certification Online certificate

What Physicians Say About ISSCA Events

Real feedback from past conference attendees.

Pre-sale open

Lock In Pre-Sale at $1,090

Pre-sale closes September 30, 23:59 UTC. Price rises to $1,490 on October 1 — no exceptions.

$1,490

$1,090 USD

Or 3 monthly installments of $379

Pre-sale ends in: calculating...
  • 11 modules taught by ISSCA international faculty
  • 30 hours of expert-led video content
  • Self-paced learning — start the moment you enrol
  • Online assessment + serialized ISSCA certification
  • 1 year ISSCA Membership + App + Magazine ($1,000 value)
  • Lifetime access · future updates included

+ Bonus downloads included

  • Clinical Case Studies PDF
  • ISSCA Regenerative Protocols Kit
  • COA Reading Reference Guide
  • Routes of Administration Reference
  • Protocol Algorithm by Indication
  • Cellgenic Product Catalog 2026
Enroll Now — USD 1,090 Enroll with ISSCA Membership — USD 1,817.50 Adds 12 months of Global Membership and takes 25% off the certification — the program at $817.50 + membership at $1,000

Secure checkout · 14-day guarantee

14-day guarantee

If you haven't started, you don't pay.

14 days from your purchase. As long as you haven't begun Module 1, request a full refund — no questions, no friction. Once you've started, you've taken the value. We protect the work, not the bypass.

Frequently Asked Questions

Master the Present of Medicine

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