01 · MSC vs Exosome
The decision matrix
When MSCs outperform, when exosomes are equivalent or better, and the indications where the regulatory delta makes the choice for you.
🇲🇽 ISSCA Global Summit · Cancún · Sept 25–27, 2026 · Physicians Only
Advanced MSCs & Exosome Certification.
Master mesenchymal stem cells, exosomes and the secretome — sourcing standards, dose-by-indication matrices, nebulized exosomes, MOTS-C and cell-free protocols, with supervised hands-on lab practice and a live clinical demonstration. Your pass includes the full 2-day ISSCA Global Summit conference: keynotes, 24 clinical faculty and 12,000+ physicians from 45+ countries.
The Full Summit Experience · Physicians Only
Your pass is the certification and the entire Summit.
Your pass spans the JW Marriott Cancún weekend: your Advanced MSCs & Exosome certification day at Cellgenic Lab, plus the full 2-day ISSCA Global Summit conference — NYT-bestselling keynotes (Josh Axe · Ben Azadi), 24 clinical faculty and 12,000+ physicians from 45+ countries.
2-Day Summit · + Certification
Cellgenic Lab · Cancún
ISSCA · Certification
Included
Certification + 2-Day Summit
Your Advanced MSCs & Exosome certification day, plus the 2-day ISSCA Global Summit conference with world-class speakers at the JW Marriott Cancún.
Included
MSCs & Exosome Certification
Clinical protocols for mesenchymal stem cells, exosomes and the secretome — sourcing, dose-by-indication, and real clinical case frameworks (Hashimoto's, stroke, radiculopathy).
Included
Networking & MedConnect Social
Connect with faculty and peers during structured breaks and the MedConnect rooftop social. Coffee and lunch included with your registration.
Included
Hands-On Lab & Demo Patient
Supervised hands-on practice — cell & exosome lab handling (thawing) and a live clinical demonstration with a demo patient.
Included
ISSCA Certification
Official ISSCA Advanced MSCs & Exosome Certification — faculty-signed and internationally recognized in 45+ countries.
Included
Advanced Technology Integration
Combine MSCs and exosomes with IV therapies, photobiomodulation, PEMF/HBOT and AI diagnostics for measurable patient outcomes.
— 02 / What you'll master
Six skills you walk out with.
By 6 PM Sunday you can confidently choose between MSCs and exosomes, source from a vetted partner, dose by indication, and monitor outcomes that contribute to the field's evidence base.
02 · Sourcing
Donor-screening checklist
Tissue source (umbilical cord vs adipose vs bone marrow), donor screening, characterization standards, batch testing and cold-chain logistics.
03 · Indication Mapping
Dose-by-indication matrix
A printable matrix: indication → MSC vs exosome → cell count or particle count → route → schedule. The matrix our faculty actually uses.
04 · Routes & Schedules
IV · IA · IT · topical
Route by indication, infusion-rate protocols, premedication, booster timing, and the scenarios where route changes outcome.
05 · Safety & Documentation
AE protocol + paperwork
Watch-list at hour 1, day 1, week 1, month 1. Escalation pathway. Consent forms, intake forms, the documentation trail that protects your clinic.
06 · Outcome Tracking
Registry & reporting
How to enter outcomes into the ISSCA registry, the minimum dataset, and how that contributes to the field-wide evidence the clinic needs.
— The Curriculum
The complete MSCs & exosome curriculum.
From cell-free regeneration fundamentals to confident clinical protocols — six modules, structured for working physicians.
The science under every protocol: how mesenchymal stem cells and exosomes work, how they are sourced, and the evidence base that validates clinical use.
- Cell-based vs cell-free regeneration · the secretome
- Allogeneic vs autologous sourcing & donor screening
- Exosome & extracellular-vesicle biology, paracrine signaling
- Scientific validation, potency & characterization
From vial to patient: building reproducible, indication-specific dosing and the routes that match the clinical target.
- Dose-by-indication matrices
- Routes: IV, local, nebulized · thawing & handling
- Patient selection & biomarkers
- Storage, traceability & GMP standards
Where exosomes and MSCs move the needle on metabolic resilience, recovery and healthspan.
- Metabolic recovery protocols
- Longevity & healthspan strategies
- Mitochondrial & cellular-energy support
- Combination with MOTS-C and metabolic peptides
Immune modulation in practice — including real autoimmune cases such as Hashimoto's thyroiditis.
- Immune modulation & systemic inflammation
- Hashimoto's thyroiditis: exosome + peptide stack
- Gut-immune axis & mucosal health
- Post-viral and chronic-inflammatory states
Clinical protocols across the indications clinicians ask for most — neuro and MSK.
- Ischemic stroke with neurological sequelae · nebulized exosomes
- Low back pain & lumbar radiculopathy
- Joint, tendon & soft-tissue regeneration
- Recovery & functional rehabilitation integration
Turning single tools into powerful clinical systems — exosomes and MSCs alongside IV therapies and regenerative technology.
- IV peptide & nutrient integration
- Combination with photobiomodulation, PEMF/HBOT
- AI diagnostics & objective outcome tracking
- Designing multimodal regenerative protocols
Upon completing the certification, physicians receive their official ISSCA Advanced MSCs & Exosome Certification — internationally recognized and backed by 17 years of ISSCA's global education ecosystem.
- ISSCA Advanced MSCs & Exosome Certificate — internationally recognized
- Complete clinical protocol package: real cases, forms and resources
- Priority access to advanced ISSCA app resources and global medical community
- Ongoing access to webinars, updated protocols and ISSCA events
— 03 / The Full Agenda
Your certification + the 2-day Summit.
Your MSCs & Exosome certification day at Cellgenic Lab, plus the 2-day ISSCA Global Summit conference — all included. Switch days below.
Certification Day · Advanced MSCs & Exosome
Cellgenic Laboratory, Cancún · physicians only · hands-on lab + clinical protocols + certificate ceremony + clinic tour
Summit Day 1 · The Main Conference
Saturday, Sept 26 · Mainstage · 2 keynotes + full clinical faculty + Q&A panel + MedConnect Social
Summit Day 2 · Conference + Specialty Certifications
Sunday, Sept 27 · Mainstage morning + closing · parallel specialty certifications
— 04 / Faculty
Three clinician-scientists, Limited.
A 1:8 faculty-to-attendee ratio — the most intimate cohort on the summit. Every attendee leaves with two of their own cases reviewed by faculty.
Dr. Keith L. March, MD, PhD
Lead Faculty · Cell-Free Regenerative Therapies
Pioneer of cell-free regenerative therapeutics — coined the term "secretome." Decades of translational research on what MSCs secrete and how to deliver the payload without the cell.
Dr. Andrea Lapeire
Faculty · Group 1 · Clinical Implementation
Argentina's leading regenerative-medicine clinician with deep MSC and exosome practice. Leads Group 1 hands-on at Cellgenic Lab.
— 05 / Recognition
Earn your official ISSCA certification.
Faculty-signed, registered in the ISSCA member portal, recognized by 12,000+ ISSCA-certified physicians across 45+ countries.
Official Certification
ISSCA Accredited
Global Recognition
45+ countries
Faculty-Signed
March · Lapeire
Day 3 · Track
Sunday Sept 27 · Included
Hands-On Practice
1 Day · Clinical
Limited
First Verified, First Confirmed
Join 12,000+ certified physicians worldwide
ISSCA-accredited · 45+ countries · Faculty-signed by March · Lapeire
— Certification
Earn your official ISSCA certificate.
Upon completing the certification, you receive the official ISSCA Advanced MSCs & Exosome Certification — issued to licensed physicians and backed by 17+ years of global clinical education.
Recognized in 45+ countries
ISSCA is a global medical education organization with 17+ years of experience and a network of 12,000+ certified physicians across multiple specialties.
Physician-level certification
Issued exclusively to licensed physicians (MD/DO). MSC and exosome therapy are physician-prescribed — patient workup, dosing and escalation belong with a licensed physician.
Post-certification continuity
Certified physicians gain ongoing access to updated clinical protocols, the ISSCA app, live webinars and a global network of peers — advancement that continues beyond the event.
Part of the ISSCA education ecosystem
Your certification connects you to a long-term system — protocols, technology updates and an international network actively applying regenerative medicine in practice.
— The ISSCA Global Network
17 Years. One Global Standard.
12,000+
12,000+ physicians certified across 45+ countries in 17 years of ISSCA education. When you complete this certification, you join the world's most respected regenerative medicine network.
— Testimonials
What Physicians Say About ISSCA Events
Since 2010, ISSCA has trained 12,000+ physicians across 45+ countries. Hear directly from peers who already apply these protocols in their clinics.
— 06 / Pricing
Choose your path. Limited. Physicians only.
Reserve now with a $1,000 deposit to secure your seat, or take the full Early Bird certification — every benefit included — before it closes July 15, 2026.
Early Bird closes July 15, 2026
—Days
—Hours
—Min
—Sec
Secure Your Spot
After July 15 · balance due before Sept 27, 2026
$1,000
- Locks in your physician seat today
- Holds your place before Early Bird sells out
- $2,500 balance due before the event
Full certification benefits unlock with the Early Bird package →
Reserve — $1,000 →MSCs & Exosomes Certification
Early Bird closes July 15, 2026 · Day 3 · Sunday, Sept 27
$2,500 $3,500
Included
2-Day Conference Pass
Saturday + Sunday mainstage access.
Exclusive
Day-3 Hands-On Certification
Live demos, protocol design & real cases.
Outcome
Official ISSCA Credential
Certification-backed, not attendance only.
Everything included
Official international ISSCA credential
Clinical materials, uniform & kit
Protocol and case-study books
Certification slides and academic material
4 ISSCA Magazine editions
Priority access to advanced app resources
Sunday certification participants receive Saturday's full conference recordings. Bundle with the full Global Summit pass at checkout to attend Saturday in person.
— 09 / Venue & Logistics
JW Marriott Cancún
Oceanfront Resort & Spa · Zona Hotelera, Quintana Roo, México
Venue Address
JW Marriott Cancún Resort & Spa
Km 14.7, Blvd. Kukulcán 40
Zona Hotelera, 77500 Cancún
Quintana Roo, México
~20–30 min
28–32°C
Need a Visa Letter?
Contact info@stemcellsgroup.com with your passport details after registration. Direct flights from USA, Canada, Mexico, Colombia, Argentina, Spain, Italy, Portugal and UAE.
— 08 / FAQ
Common questions.
MSC and exosome therapy are physician-prescribed cellular therapies. Patient workup, dosing decisions and adverse-event escalation belong squarely with a licensed MD or DO. The Limited cap protects the 1:8 faculty-to-attendee ratio that makes the case-review block actually work for every attendee.
Sourcing varies by jurisdiction. The certification covers the regulatory landscape and lists the vetted sourcing partners ISSCA faculty work with. We'll cover your country's framework explicitly during sourcing & standards.
Yes — the day includes supervised hands-on practice: cell & exosome lab handling (thawing) and a live clinical demonstration with a demo patient during the clinic tour, all under faculty supervision. Paired with patient case-work, dosing matrices and safety drills.
No — the certification builds from foundations (mechanisms, sourcing, scientific validation) up to advanced protocols, so physicians new to cell-free regeneration and experienced clinicians both leave with deployable clinical systems.
Full refund until May 31. 50% refund June 1 – Aug 1. Non-refundable after Aug 1. Free transfer to another physician at your clinic up to 14 days pre-event. Force-majeure: credit carried to the next ISSCA event.
Yes — your pass includes the full 2-day Summit conference, so you attend Saturday's mainstage keynotes in person (Sunday you're in the certification lab at Cellgenic).
Combine & Save
Upgrade your experience — get 15% off both certifications.
Pair this certification with one of the parallel tracks running on the complementary day. The 15% bundle discount applies to your full enrollment.
— Day 3 · Sunday, Sept 27
Limited. Physicians only. Early Bird closes July 15.
The most intimate cohort of the summit — three of the field's leading clinician-scientists, your patient cases, the protocols.